About us

"NAPOLY" is changing the rules of the game when it comes to wound management.
We develop, produce and sell ChitoPran® bioplastic materials that never have to be removed;
they are bio-absorbed. The company provides a full cycle of production in Russia, using its own
patented technologies. "NAPOLY" is a seed company of RVC Seed Fund.

products

ChitoPran® allows affected areas to quickly recover from the wounds of various etiologies: burns, pressure sores and ulcers. ChitoPran® bio-absorbes, easily elutes while wound bathing or dissevers with a scab. There is no need to remove the material. This relieves the patient from pain and additional injury to the wound surface.

HitoPran

ChitoPran®

ChitoPran® is based on сhitosan nanofibers. Its efficacy attributes to the following factors:
• chitosan promotes activation of macrophages in the lesion and accelerates the proliferation of fibroblasts and epidermal keratinocytes
• chitosan binds and inactivates matrix metalloproteinases and protects growth factors
• the nanofibrous structure mimics the extracellular matrix and promotes the migration and growth of own cells
Ultra HitoPran

New generation of ChitoPran®.

We developed and registered five novel articles that have already clinically proven their efficacy. They contain bioadditives , greatly expand the indications for use and further possess all the unique properties of the first generation.
CHITOPRAN® WITH CIPRO provides antimicrobial action, indicated for plain risk-infected wounds.
CHITOPRAN® WITH COLLAGENASE optimizes and relieves scar formation
CHITOPRAN® WITH TRYPSINE is indicated to remove traces of necrotic tissues and fibrin
CHITOPRAN® WITH COLLAGEN combines the advantages of collagen matrix with ChitoPran
CHITOPRAN® WITH POLYPRENOLS is indicated specially to cure trophic ulcers
HitoPran 2

ChitoPran®

ChitoPran® is based on сhitosan nanofibers. Its efficacy attributes to the following factors:
• chitosan promotes activation of macrophages in the lesion and accelerates the proliferation of fibroblasts and epidermal keratinocytes
• chitosan binds and inactivates matrix metalloproteinases and protects growth factors
• the nanofibrous structure mimics the extracellular matrix and promotes the migration and growth of own cells
Ultra ChitoPran 2

New generation of ChitoPran®.

We developed and registered five novel articles that have already clinically proven their efficacy. They contain bioadditives , greatly expand the indications for use and further possess all the unique properties of the first generation.
CHITOPRAN® WITH CIPRO provides antimicrobial action, indicated for plain risk-infected wounds.
CHITOPRAN® WITH COLLAGENASE optimizes and relieves scar formation
CHITOPRAN® WITH TRYPSINE is indicated to remove traces of necrotic tissues and fibrin
CHITOPRAN® WITH COLLAGEN combines the advantages of collagen matrix with ChitoPran
CHITOPRAN® WITH POLYPRENOLS is indicated specially to cure trophic ulcers

CHITOPRAN® PROMOTES HEALING OF THE WOUNDS OF DIFFERENT ETIOLOGIES: BURNS, PRESSURE ULCERS AND VENOUS ULCERS

EASILY MODELS ON A WOUND SURFACE

IT PROVIDES A FUNDAMENTALLY NEW APPROACH TO THE MANAGEMENT OF WOUNDS. MATERIAL BIO-ABSORBS , EASILY ELUTES WHILE WOUND BATHING OR DISSEVERS WITH A SCAB. NO NEED TO REMOVE THE MATERIAL - THIS SAVES A PATIENT FROM PAIN AND FURTHER INJURY OF THE WOUND SURFACE

PROVIDES COMFORTABLE AND PAINLESS HEALING

CONVINIENT USE BY DOCTORS

CHITOPRAN® STRUCTURE CREATES CONDITIONS FOR EXCELLENT BREATHABILITY AND MOISTURE EVAPORATION THAT ENSURES MAXIMUM SAFETY AND COMFORT OF THE WOUND BED

ACCELERATES HEALING.
MAKES A PATIENT REHABILITATE QUICKER

ChitoPran product
It has been used successfully for the treatment.

ChitoPran® was successfully used to cure burns of ii – iiia degrees, trophic ulcers, bedsores frostbites. It used by doctors in hospitals and by end-users at home. Find more information and download> download volokno

ChitoPran product
It has been used successfully for the treatment.

ChitoPran® was successfully used to cure burns of ii – iiia degrees, trophic ulcers, bedsores frostbites. It used by doctors in hospitals and by end-users at home. Find more information here and download> download volokno
The company was founded in April 2014 with the participation of
RVC Seed Fund and the Scientific Park of MSU
In August, 2014 the company received a registration certificate for the first generation of ChitoPran®
Since November, 2014 "NAPOLY" is involved in the distribution of plasters and dressings produced by "New Bandaging Materias" LLC. The key products of "New Bandaging Materias" LLC were developed together with «NAPOLY» founders
In October 2014, the founders outlicensed the patent for the first generation of ChitoPran® to the compаny
In October 2014, "NAPOLY" was named «The best project in biotechnology» in the "Innopraktika" exhibition
In September, 2015 we completed R&D for the second generation of ChitoPran® and started the registration procedure
In March,2016 "NAPOLY" was named «The startup of 2015» in the «Biotech» sphere in Russia
In March, 2016 the R&D on ChitoPran® with growth factors started
In October, 2016 we received two registration certificates for the second generation of ChitoPran®
In November, 2016 we obtained new patent
In November, 2016 - February, 2017 first international steps are done – "NAPOLY" exhibited its products in MEDICA 2016 and ARAB HEALTH 2017 events

Manufacturing

"NAPOLY" established full cycle production of ChitoPran® in Russia. Using our patented technologies we produce nano- and micro-fibers and the materials based on them with a very high production capacity. We developed and patented the compositions of the spinning solutions and the technoogy conditions that ascertain the unique properties of the material:

  • morphology of the fibrous layer that mimics the extracellular matrix and enables the rapid movement and growth of its own epithelium;
  • high vapor and air permeability;
  • high bioavailability of bioadditives, which allows to reduce their dosage, and hence toxicity.

Innovations

NAPOLY is changing the rules of the game when it comes to wound dressing. We develop, produce and sell ChitoPran® dressings that never have to be removed; they are bio-absorbed.

The performance is based on:
the biological activity of chitosan which is able to activate macrophages, enhance the proliferation of fibroblasts, accelerate growth of epidermal keratinocytes, bind and inactivate matrix metalloproteinases – inflammation enzymes;
the special structure of the nanofibers that mimic the structure of the extracellular matrix and contribute to the growth of the cells.

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NAPOLY LLC

123458 Moscow
Tvardovskogo st., 8/1

Tel.: +7 (495) 765-56-92

E-mail: info@napoly.info